Introducing PureAire Monitoring Systems latest product - the PureAire CloudConnect module

 

PureAire Monitoring Systems is excited to announce the launch of our latest offering—the PureAire CloudConnect module, provides for internet connectivity (with Cloud storage capabilities) for our full line of Oxygen and Carbon Dioxide Monitors, as well as our Toxic and LEL Combustible Gas Detectors. Our new CloudConnect module will send continuous gas concentration data to a secure Cloud storage space, and will provide immediate alarm and system information to customer-designated safety personnel via text, phone call, or email.

By utilizing the CloudConnect module, PureAire customers will be able to remotely monitor oxygen or other gas levels 24/7, and receive real-time alerts when gas concentration levels require attention, allowing them to identify and respond to potential safety concerns before accidents occur.

All monitoring data will be stored safely and securely in the Cloud, retrievable for viewing anytime, and configurable for compliance reporting.

Biorepository Safety

 

What is a Biorepository?

A biorepository, or "biobank",  is a specialized facility designed to store, archive, and distribute biological samples for research or clinical purposes. Biorepositories house biological samples, such as blood, plasma, urine, saliva, tissues, DNA, and organs, among other specimen types, collected from consenting individuals. Critical associated information, including relevant health information about the donor, is linked to the sample, given a unique identifier, and uploaded into a laboratory information management system. Scientists use samples stored in biorepositories to research diseases and develop new treatments, drugs, and vaccines, among other applications. Biorepositories provide secure environments that help ensure the integrity of the samples stored within, and allow researchers an efficient way to access the samples they need for their studies.

How are Biological Samples Stored?

Cryopreservation is the most commonly used method for freezing and storing biological samples.  This method most often uses liquid nitrogen (LN2) to achieve the ultra-low temperature necessary for cryopreservation, usually between -80°C and -196°C. Biorepositories use cryogenic freezers and LN2  to achieve and maintain the super-cold temperatures required for long-term sample storage.

Biorepositories must rely on a continuous supply of LN2 to ensure that samples stay fully frozen in order to preserve their integrity and usability. Liquid nitrogen is typically supplied through liquid nitrogen generators or bulk tanks located outside the facility, or from cryogenic cylinders or Dewar vessels located inside near the freezers.

Liquid Nitrogen Safety - Oxygen Monitors Can Reduce Risk

Cryopreservation ensures that the samples remain viable for future use. However, since LN2 is an oxygen-depleting gas that is both odorless and colorless, absent appropriate monitoring, biorepository personnel would be unable to detect a liquid nitrogen leak if one were to occur in a gas cylinder or supply line. When there is not enough oxygen in the air, persons working in the area can become disoriented, lose consciousness, or even suffocate from lack of oxygen. Additionally, a liquid nitrogen leak could lead to the loss of its super-cooling properties, causing the temperature to rise inside the freezer, possibly causing catastrophic damage to the biological samples.

As such, best practice calls for oxygen deficiency monitors to be installed anywhere there is a risk of nitrogen gas leaks. The National Institutes of Health’s Design Requirements Manual stipulates that, to warn of oxygen depletion, oxygen monitoring equipment is to be provided in freezer rooms and other rooms where cryogenic fluids (including liquid nitrogen) are supplied or stored.

PureAire Monitors

PureAire Monitoring Systems’ Oxygen Deficiency Monitors continuously track levels of oxygen and will detect liquid nitrogen leaks before freezer failure jeopardizes either the integrity of stored samples or employee health. Built with zirconium oxide sensor cells to ensure longevity, PureAire’s O2 Monitors can last, trouble-free, for over 10 years under normal operating conditions.  In the event of an LN2 gas leak, and a decrease in oxygen to an unsafe level, our Monitor will set off an alarm, complete with horns and flashing lights, alerting employees to evacuate the affected area.

The Oxygen Monitors should be placed wherever liquid nitrogen is stored, and in all rooms and areas where nitrogen is used.

PureAire Oxygen Monitors measure oxygen 24/7, with no time-consuming maintenance or calibration required.

Each PureAire O2 Monitor has an easy to read screen, which displays current oxygen levels, for at-a-glance readings by biorepository personnel, who derive peace of mind from the Monitor’s presence and reliability.

Sterilizing Medical Devices Using Ethylene Oxide

 

According to the Centers for Disease Control and Prevention, 48.3 million procedures were performed at hospitals and ambulatory surgery centers in the United States in 2010. Healthcare providers and patient advocates understand that infection prevention requires meticulous sanitation and sterilization of all facilities, equipment, and instruments used in surgery settings. According to the World Health Organization, post-operative infections contribute to patients’ spending extra days in the hospital, at a cost of some $900 million per year. Medical devices that are sterilized to eliminate potentially harmful pathogens and microorganisms are critical to delivering safe and cost-effective patient outcomes.

Medical Device Sterilization

Sterilization is to thoroughly clean and disinfect medical and surgical devices in order to prevent infection by killing any microorganisms (i.e., bacteria, viruses, or fungi) that might otherwise be present in the devices, and that could pose significant risks to patients.

There are a variety of sterilization methodologies in use in the healthcare industry (including, among others, steam under pressure/autoclave, dry heat, ultraviolet radiation, and gas vapors), and the most effective sterilization process in a given situation may depend on the specific type of device subject to sterilization. That is, sterilization of medical and surgical devices works best when proper techniques are used on the appropriate devices.

By way of example, high-temperature steam autoclave is the oldest sterilization technique in the medical equipment industry, and it is extremely safe, but it is not well-suited for instruments that are sensitive to prolonged exposure to heat and/or moisture. For instance, the buildup of water droplets (as a result of high-temperature steam autoclave sterilization) inside device components can corrode materials that should not be exposed to water. Likewise, instruments with plastic or electronic components could become damaged when exposed to high temperatures and steam

Sterilization Using Ethylene Oxide Gas

The use of ethylene oxide gas (EtO) has become a practical alternative to medical device sterilization via steam autoclave.

EtO was first used as a chemical sterilant in the 1950s and, since then, low-temperature EtO gas sterilization has become one of the more commonly used sterilization methods in the healthcare industry.  According to the Ethylene Oxide Sterilization Association, ethylene oxide is used to sterilize over 20 billion medical devices each year in the U.S., representing over 50% of the medical devices and nearly 90% of the surgical kits used by the healthcare industry.

EtO is a preferred sterilization method in large part because, given its low-temperature application, it will not damage medical equipment, complex implantable devices, surgical kits, and other instruments that require sterilization. Ethylene oxide has a wide range of material compatibility; it is suitable for use on materials that cannot tolerate heat, moisture, or abrasive chemicals, such as electronics, plastic, paper, and rubber, and the gas can penetrate small spaces inside the devices, and can even sterilize  medical instruments that have  already been packaged in plastic.

Protecting Employees Working in EtO Device Sterilization Environments

While ethylene oxide sterilization is widely used in sterilizing medical and surgical devices, there are concerns about the potential negative effects on employees working with EtO, since personnel and property are exposed to the possibility of leaks from gas supply lines and storage containers. Long-term exposure to ethylene oxide can irritate the eyes, skin, nose, throat, and lungs, and harm the brain and nervous system, and it has been linked to cancer.

Ethylene oxide is a highly combustible, flammable, and colorless gas that has a sweet, ether-like odor at toxic levels. However, the odor’s presence and strength cannot be relied upon to ensure safety; therefore, absent appropriate monitoring to detect that a leak or an or an accumulation of ethylene oxide has occurred, sterilization employees could face serious health risks from working in enclosed, poorly ventilated areas.

Best practices when working with EtO include, but not limited to, the use of goggles, protective clothing, and the installation of gas monitoring systems. The National Fire Protection Association (NFPA) recommends installing gas detection monitors in all areas where EtO is used. According to the NFPA, the gas monitors should provide audible and visual warnings to indicate when concentrations of ethylene oxide exceed a level of 25% of the lower limit of flammability of ethylene oxide. Furthermore, the gas detection system should automatically shut off the flow of gas and automatically turn on the buildings’ ventilation system.

PureAire Monitors

PureAire Monitoring System's ST-48 Ethylene Oxide (EtO) Combustible Gas Monitor offers continuous gas monitoring at medical sterilization facilities. The monitor is housed in a NEMA 7 explosion proof enclosure specifically designed to prevent an explosion and suitable for Class 1, Divisions 1 & 2, Groups A,B, C, and D.

PureAire’s EtO Combustible Gas Monitor features an easy to read screen, whichdisplays current gas levels for at-a-glance observation by employees, who derive peace of mind from the monitor’s presence and reliable performance. In the event that ethylene oxide reaches an unsafe level, PureAire’s monitors will set offalarms, complete with horns and flashing lights, alerting personnel to evacuate the area. At the same time, the monitors can be programmed to turn off the flow of gas, and turn on the ventilation system.

Liquid Nitrogen Dosing – Supporting Non-Carbonated Beverage Packaging, One Bottle At A Time

 

To create that perfect glass of wine, refreshing sip of water, or other non-carbonated drinks of choice, beverage producers often turn to liquid nitrogen (LN2).Liquid nitrogen fills an important role in the bottling and canning of non-carbonated beverages.

What is Liquid Nitrogen?

Liquid nitrogen is a cryogenic, liquefied form of nitrogen (N). Nitrogen is an oxygen-depleting gas that is a liquid at temperatures below −195.8° Celsius(−320.4° Fahrenheit).  At those low temperatures, liquid nitrogen is so cold that it immediately freezes. When LN2 is exposed to the air and begins to warm, it vaporizes, changing from its liquid state back to nitrogen gas.

The properties of LN2 are of particular importance to bottlers. Liquid nitrogen is an inert, odorless, and colorless gas that does not react to other substances or add unwanted flavors, odors, or colors to beverages. This ensures that products taste as they should.

Liquid Nitrogen Dosing

Liquid nitrogen dosing is a process by which, after filling the beverage container, and just before sealing it, beverage packagers dispense a precise amount of LN2 into the space (the “headspace”) between the product and the top of the bottle or can. Exposure to ambient air causes the liquid nitrogen to warm, and vaporize into nitrogen, which displaces residual oxygen and pressurizes the container.

Displacing or removing oxygen from beverage containers prevents unwanted oxidation, the presence of which can negatively impact product quality and shorten product shelf-life. Moreover, pressurizing plastic bottles and aluminum cans by introducing liquid nitrogen may improve the structural integrity of the beverage containers, and their improved durability might enable bottlers to use lighter, thinner containers, which could be both economical and environmentally friendly.

Liquid Nitrogen Safety

Liquid nitrogen usage, though important for bottling and packaging, is not without risk.

When liquid nitrogen is exposed to air (including during dosing), it evaporates, changing from a liquid to an oxygen-depleting nitrogen gas. Oxygen deprivation can put employees in real danger if there are leaks from LN2 dosing equipment or on-site gas cylinders. In the event of a liquid nitrogen leak, workers could become disoriented, lose consciousness, or even suffocate from breathing oxygen-deficient air. Since LN2 is both scentless and colorless, workers would, in the absence of appropriate monitoring, have no way of knowing that there has been a liquid nitrogen leak.

However, by utilizing a PureAire oxygen deficiency monitor, personnel can safely track oxygen levels and detect leaks before workers’ health is jeopardized. Best practice calls for oxygen deficiency monitors to be installed anywhere there is a risk of liquid nitrogen gas leaks. Monitors should be placed wherever liquid nitrogen is stored, and in all areas where liquid nitrogen is used. The monitoring equipment should include visual and audible alarms that would be activated in the event of liquid nitrogen leaks and a decrease in oxygen levels.

PureAire Oxygen Deficiency Monitors

PureAire Monitoring Systems’ complete line of Oxygen Deficiency Monitors offers thorough air monitoring, with no time-consuming maintenance or calibration required. A screen displays current oxygen levels for at-a-glance reading by employees, who derive peace of mind from the Monitor’s presence and reliable performance.

In the event of a  liquid nitrogen leak, and a decrease in oxygen to an unsafe level, PureAire’s Monitor will set off an alarm, complete with horns and flashing lights, alerting personnel to evacuate the area.

PureAire’s Monitor will remain accurate at extremely low temperatures. That makes the Monitor ideally suited for facilities using liquid nitrogen, such as bottling and packaging plants. Built with zirconium oxide sensor cells to ensure longevity, PureAire’s Oxygen Monitors can last, trouble-free, for over 10 years under normal operating conditions.

PureAire Introduces New 0-10ppm Trace Oxygen Analyzer, with Low ppb Accuracy

 

PureAire Monitoring Systems is excited to add its 0-10 parts per million(ppm) Trace Oxygen Analyzer to our full line of Oxygen Deficiency Monitors, Carbon Dioxide Monitors, Toxic Gas Detectors, and LEL Gas Monitors. The new Analyzer measures trace levels of oxygen across a wide variety of applications where precise, ultra-low gas concentration monitoring is critical to ensure safety and product quality.

Our new Trace Oxygen Analyzer provides accurate measurements of trace oxygen levels from 0-10ppm. The Analyzer’s repeatability and accuracy are <± 2% parts per billion (ppb) of the calibrated range. It is well suited for the semiconductor industry, including wafer transfer tools, process chambers, and Organic Light Emitting Diode (OLED) manufacturers, as well as 3D printing, pharmaceutical development, manufacturing, and packaging. PureAire's low ppm and ppb sensors are ideal for any applications where inert gases, including, but not limited to, nitrogen, helium, and argon are used to displace oxygen as part of the oxidation-reduction process.

PureAire’s Trace Oxygen Analyzer is designed for continuous monitoring where inert gases are used to create environments in which there is little to no oxygen present. It has a remote sensor that, with the use of a KF-type vacuum fitting, mounts directly into gloveboxes or process/vacuum chambers, and it allows for monitoring up to 10 feet away from the Analyzer.

The Near Absence of Oxygen Helps Protect Product Integrity in a Variety of Industrial Applications

The presence of oxygen in certain manufacturing processes can negatively affect the integrity of products. For instance:

• Semiconductor manufacturers seek to eliminate oxygen during key processes to protect the quality and reliability of sensitive components. The presence of trace impurities can result in the loss of whole batches of wafers.
• High-purity gas systems, laboratories, and pharmaceutical facilities require sterile, oxygen-free conditions in order to test, manufacture, package, and deliver pure, contaminant-free gases, drugs, and medicines.
• Food packagers and bottlers know that residual oxygen can promote the growth of microorganisms such as mold and other pathogens, potentially leading to foul tastes, off-textures, and shortened shelf-life of food and beverage products and, in certain instances, food-borne illnesses.

PureAire Trace Oxygen Analyzer

PureAire’s Trace Oxygen Analyzer should be used in any location where precise measurements of oxygen levels need to be maintained, and where the presence of oxygen could negatively affect product integrity.

Our Analyzer responds in seconds to changes in oxygen levels, and in the event of an unacceptable deviation in required O2 levels, will set off an alarm, complete with horns and flashing lights, alerting personnel to take corrective action.

PureAire’s durable, non-depleting, long-life zirconium oxide sensor will remain accurate over a wide range of temperature and humidity levels, and it will last for 10+ years in a normal environment without needing to be replaced.

PureAire Introduces New 0-100 ppm Trace Oxygen Analyzer

 

PureAire Monitoring Systems is excited to add its 0-100 parts per million(ppm) Trace Oxygen Analyzer to our full line of Oxygen Deficiency Monitors, Carbon Dioxide Monitors, and Combustible/Toxic Gas Detectors. The new Analyzer measures trace levels of oxygen across a wide variety of applications that require real-time, ultra-low gas concentration monitoring to ensure safety and product quality.

PureAire’s Trace Oxygen Analyzer is designed for continuous monitoring where inert gases are used to create environmentsin which there is little to no oxygen present. It has a remote sensor that, with the use of a KF type vacuum fitting, mounts directly into gloveboxesor process/vacuum chambers, and it allows for monitoring up to 10 feet away from the Analyzer.

Our new Trace Oxygen Analyzer is capable of measuring oxygen levels from 0-100 ppm. It is well suited for the semiconductor industry, including wafer transfer systems, process chambers, and Organic Light Emitting Diode (OLED) manufacturers, as well as 3D printing, welding, pharmaceutical development, manufacturing, and packaging, and for any applications where inert gases, including, but not limited to, nitrogen, helium, and argon are used to displace oxygen.

The Near Absence of Oxygen Helps Protect Product Integrity in a Variety of Industrial Applications

The presence of oxygen in certain manufacturing processes can negatively affect the integrity of products. For instance:

• Semiconductor manufacturers seek to eliminate oxygen during key processes to protect the quality and reliability of sensitive components.
• High-purity gas systems, laboratories, and pharmaceutical facilities require sterile, oxygen-free conditions in order to test, manufacture, package, and deliver pure, contaminant-free gases, drugs, and medicines.
• Food packagers and bottlers know that residual oxygen can promote the growth of microorganisms such as mold and other pathogens, potentially leading to foul tastes, off-textures, and shortened shelf-life of food and beverage products and, in certain instances, food-borne illnesses.

PureAire Trace Oxygen Analyzer

PureAire’s Trace Oxygen Analyzer should be used in any location where precise measurements of oxygen levels need to be maintained, and where the presence of oxygen could negatively affect product integrity.

Our Analyzer responds in seconds to changes in oxygen levels, and in the event of an unacceptable deviation in required O2levels,will set off an alarm, complete with horns and flashing lights, alerting personnel to take corrective action.

PureAire’s durable, non-depleting, long-life zirconium oxide sensor will remain accurate over a wide range of temperature and humidity levels, and it will last for 10+ years in a normal environment without needing to be replaced.

PureAire Introduces New Dual Oxygen/Carbon Dioxide Monitor

 PureAire Monitoring Systems is excited to introduce its new Dual Oxygen/Carbon Dioxide Monitor, an important addition to our full line of Oxygen Deficiency Monitors, Carbon Dioxide Monitors, and Combustible/Toxic Gas Detectors.  Our new Monitor is designed for continuous monitoring of oxygen and carbon dioxide levels  across a wide variety of applications, including cryogenic facilities, breweries, food processing plants, cannabis grow rooms, pharmaceutical manufacturing operations, laboratories, hospitals, and universities.

Our Dual Monitor can sample O₂/CO₂ levels from up to 100 feet away and is ideal for facilities that use inert gases, including, but not limited to, nitrogen, helium, and argon. Its NEMA 4X/IP66 dust-tight and water-tight enclosure will protect the Monitor against dust, water, and damage from ice formation.

PureAire’s new Dual O₂/CO₂ Monitor continually measures oxygen levels from 0-25%, and carbon dioxide levels from 0-50,000 parts per million (ppm), with both O₂ and CO₂ measurements readily visible on the Monitor’s easy-to-read backlit displays. Depending on our customers’ specific requirements, the Monitor can be linked to a programmable logic controller (PLC), a multi-channel controller, or tied into building systems themselves.

The new O₂/CO₂ Monitor features dual built-in LED visual alarms, two alarm level set-points for both O₂ and CO₂, as well as two relays for each monitored gas. The Monitor responds in seconds to changes in oxygen and carbon dioxide levels, and it will remain accurate over a wide range of temperature and humidity levels.

PureAire’s Dual Oxygen/Carbon Dioxide Monitor offers thorough air monitoring, with no time-consuming maintenance or calibration required. Built with durable, non-depleting, zirconium oxide sensor cells, and non-dispersive, infrared (NDIR) sensor cells to ensure longevity, PureAire’s Dual O₂/CO₂ Monitor can last, trouble-free, for 10+ years in normal working conditions.